Intercell´s clinical data on Japanese Encephalitis vaccine published in "The Lancet"
Geschrieben am 03-12-2007 |   
 
 Intercell´s (ICLL) Phase III clinical trial results on its  investigational Japanese Encephalitis vaccine have been published in  the renowned medical journal The Lancet The article is the first  publication describing the full clinical data to date on Intercell´s  vaccine against Japanese Encephalitis The publication details  significant safety and immunogenicity results on the ICLL vaccine,  which represents an innovative approach against a disease with a high degree of unmet medical need
 
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  research
  Wien (euro adhoc) - Vienna (Austria), December 3, 2007 - Intercell  (VSE: ICLL) is pleased to announce the acceptance of a scientific  article about its investigational Japanese Encephalitis vaccine by  the internationally-renowned scientific and medical journal "The  Lancet".
  With over 3 billion people living in endemic areas, Japanese  Encephalitis, a mosquito-borne flaviviral infection, is the leading  cause of childhood encephalitis and viral encephalitis in Asia.  Japanese Encephalitis represents a clear threat to travellers and  military personnel from industrialized countries visiting endemic  areas. The disease is usually severe, resulting in residual  neuropsychiatric sequelae in up to 50% of cases and a fatal outcome  in about 25% of all cases. No treatment is currently available, only  vaccination effectively prevents the disease. Intercell´s innovative  investigational vaccine, which is planned to enter global markets in  2008, is a purified, inactivated product for active immunization  against viral infections of Japanese Encephalitis.
  In a recently concluded Phase III non-inferiority trial, Intercell´s investigational Japanese Encephalitis vaccine demonstrated
  » Immunogenicity against Japanese Encephalitis comparable to that of  the U.S.   licensed product, JE-VAX®
  » An overall clinical safety profile similar to placebo combined with an   excellent local tolerability profile
  Intercell´s innovative investigational vaccine, which is manufactured in the company´s proprietary manufacturing facility in Scotland, is  prepared using tissue culture rather than live organisms and does not contain stabilizers such as gelatin or preservatives in its  formulation.
  The article published in "The Lancet" reports of the detailed  findings in a multicenter, multinational, observer-blinded randomized controlled Phase III non-inferiority study. The paper was written  under the lead of Intercell´s Vice President of Clinical Development  & Medical Officer, Dr. Erich Tauber, in cooperation with scientists  from the Medical University of Vienna, Austria and University of  Washington, Seattle, USA as well as the Medical University Innsbruck, Austria.
  "This publication on our vaccine means that Intercell´s approach and  the data of our study have been peer-reviewed by highly-ranked  independent scientific and medical experts, who came to the  conclusion that our innovative vaccine, if approved, will meet a  major medical need," stated Alexander von Gabain, Chief Scientific  Officer of Intercell AG. He added: "It is a valuable appreciation of  our scientific work that our data has been published in The Lancet,  which is one of the world´s leading medical journals."
  "The Lancet", which first appeared in the year 1823, is an  independent and authoritative voice in global medicine that seeks to  publish high-quality clinical trials that will alter medical  practice. "The Lancet" delivers in-depth knowledge in key medical  disciplines. (www.thelancet.com)
 
  end of announcement                               euro adhoc 03.12.2007 08:35:00 --------------------------------------------------------------------------------
 
  ots Originaltext: Intercell AG Im Internet recherchierbar: http://www.presseportal.de
  Further inquiry note:
  Intercell AG  Lucia Malfent Head of Communications Tel. +43 1 20620-303 lmalfent@intercell.com
  Branche: Biotechnology ISIN:    AT0000612601 WKN:     A0D8HW Börsen:  Wiener Börse AG / official market 
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