EANS-News: Epigenomics AG: Full Year Results for the Year Ended 31 December 2010

• Continuing to build European market and expanding beyond.
• Focus 2010/2011 on U.S. product development and FDA submission.
• Launch of Epi proColon® 2.0 in Europe planned for 2011

--------------------------------------------------------------------------------
Corporate news transmitted by euro adhoc. The issuer/originator is solely
responsible for the content of this announcement.
--------------------------------------------------------------------------------

Annual Reports/annual result/Molecular diagnostics

Subtitle: • Continuing to build European market and expanding beyond.
• Focus 2010/2011 on U.S. product development and FDA submission.
• Launch of Epi proColon® 2.0 in Europe planned for 2011

Berlin, Germany, and Seattle, WA, U.S.A., April 7, 2011 (euro adhoc)
- Epigenomics AG(Frankfurt Prime Standard: ECX), the cancer molecular
diagnostic company, today announced its full year results for the
year ended 31 December 2010 and gave an outlook on the priorities for
2011.

Key Financials 2010 and Prognosis 2011
• Revenue for the full year of EUR 1.8 million (2009: EUR 4.3 million)
generated from product sales of Epi proColon® kits and out-licensing and
partnering activities;
• Decrease in revenues is due to recognition of non-recurring revenue from
R&D support for partners in 2009;
• Costs of sales accordingly significantly dropped to EUR 0.5 million (2009:
EUR 2.8 million)
• Overall operating costs decreased by 5% in 2010 due to further
streamlining operations and commercially focused strategy execution.
• Costs for external R&D and for biological samples decreased significantly
due to the finalization of the academic PRESEPT study in Q1/2010;
• Operating (EBIT) loss increased by 12% to EUR 11.5 million (2009: EUR 10.2
million);
• Net loss for the year amounted to EUR 11.5 million (2009: EUR 10.2
million);
• Cash consumption improved with EUR 10.3 million in 2010 compared to EUR
11.3 million in 2009;
• Financial position substantially strengthened by capital increase in
Q1/2010 resulting in gross proceeds of EUR 33.1 million;
• Cash and cash equivalents at year end 2010 amounted to EUR 24.6 million in
(2009: EUR 4.0 million);
• 2011 financial guidance: EBIT, net loss and cash consumption for 2011
expected to be at similar levels compared to 2010;
• Accrued losses expected to surpass 50% of share capital in German
statutory accounts (HGB) in H2 2011 and if so, will require an
extraordinary shareholder meeting pursuant to Sec. 92 para 1 AktG (German
Stock Corporation Act).

Operational Highlights in 2010 and 2011 YTD
• Epigenomics accelerated sales of its blood-based Septin9 test, Epi
proColon®, for the early detection of colorectal cancer. The test is now
broadly available in Germany and Switzerland and the Company further
expanded its commercial network into new markets, including Austria,
France, Israel, Turkey and the Middle East. In parallel, the Company is
working towards guideline inclusion and reimbursement in Germany and other
key markets.
• The Company in 2010 significantly progressed development of its 2nd
generation colorectal cancer blood test, Epi proColon® 2.0. A prototype
demonstrated excellent clinical performance of 91% sensitivity at 87%
specificity. The new assay is easier to use, faster and compliant with FDA
manufacturing and quality requirements.
• Submission of Epi proColon® 2.0 for FDA premarket approval (PMA) in the
U.S. is planned for Q4 2011, the launch of Epi proColon® 2.0 in Europe is
expected in the same time frame.
• In parallel, the Company has started developing and implementing a
strategy to obtain U.S.-guideline inclusion and reimbursement following
the potential approval and launch of an FDA-approved Epi proColon® test in
the U.S.
• With the announcement of a new CEO of the U.S. subsidiary Epigenomics Inc.
in due course, the Company will also start building a core commercial team
to prepare the launch of a future U.S. product in the event of approval by
the FDA. The Company will inform on the new head of the U.S. operation in
a separate communication.
• Epigenomics made significant progress its lung cancer program, with a
successful launch of Epi proLung® in July 2010 in Europe. The focus is now
on building awareness and generating acceptance for the product among
European key opinion leaders through clinical studies.

Geert Nygaard, Chief Executive Officer of Epigenomics commented:

"In 2010 we have continued evolving Epigenomics into a
commercially-oriented, product-driven company, and this will continue
to be the primary aim of our strategy going forward. We have
continued to pursue a successful dual strategy with our own product,
Epi proColon®, and with our partners and their colorectal cancer
blood tests using our mSEPT9 biomarker available around the world.
After about a year in the market, we and our partners have started
seeing the first commercial traction with these products and, most
importantly, success stories of cancer cases detected by our test
that otherwise might have gone unnoticed - with potential fatal
consequences for the patients affected. Our main focus in 2011 will
be on the strategically most important U.S. market. Great progress is
being made with the development of our U.S. product and we believe we
are still on plan for filing with the FDA within 2011. We align our
activites here closely with our partner Abbott. As we are progressing
with the development of our second generation product for the U.S.
market, we have also made progress in building a commercial core team
for the U.S. and will announce a new head of our Seattle-based U.S.
operations shortly. In parallel we have initiated a project focused
on U.S. reimbursement and screening guideline recognition."

-Ends-

Conference calls for press and analysts

The complete Annual Report 2010, which was released today, can be
obtained from Epigenomics´ website at: http://www.epigenomics.com/en/
news-investors/investors/financial-reports.html.

Epigenomics will host a annual press conference in Frankfurt Main,
Germany in German language at 11 am CET today. The company will also
be hosting a conference call and audio webcast on the same day for
analysts at 3pm CET today. Details of both events will be available
on Epigenomics´ website at
http://www.epigenomics.com/en/news-investors.html.

Contact Epigenomics AG

Dr. Achim Plum
Sen. VP Corporate Development
Epigenomics AG
Tel +49 (0) 30 24345 368
pr@epigenomics.com
www.epigenomics.com

About Epigenomics

Epigenomics (www.epigenomics.com) is a molecular diagnostics company developing

and commercializing a pipeline of proprietary products for cancer.
The Company´s products enable doctors to diagnose cancer earlier and
more accurately, leading to improved outcomes for patients.
Epigenomics´ lead product, Epi proColon®, is a blood-based test for
the early detection of colorectal cancer, which is currently marketed
in Europe and is in development for the U.S.A. The Company´s
technology and products have been validated through multiple
partnerships with leading global diagnostic companies including
Abbott, QIAGEN, Sysmex, and Quest Diagnostics. Epigenomics is an
international company with operations in Europe and the U.S.A.
Epigenomics´ legal disclaimers. This communication expressly or
implicitly contains certain forward-looking statements concerning
Epigenomics AG and its business. Such statements involve certain
known and unknown risks, uncertainties and other factors which could
cause the actual results, financial condition, performance or
achievements of Epigenomics AG to be materially different from any
future results, performance or achievements expressed or implied by
such forward-looking statements. Epigenomics AG is providing this
communication as of this date and does not undertake to update any
forward- looking statements contained herein as a result of new
information, future events or otherwise.

The information contained in this communication does not constitute
nor imply an offer to sell or transfer any product, and no product
based on this technology is currently available for sale by
Epigenomics in the United States of America. The analytical and
clinical performance characteristics of any product based on this
technology which may be sold at some future time in the U.S.A. have
not been established.

end of announcement euro adhoc
--------------------------------------------------------------------------------

ots Originaltext: Epigenomics AG
Im Internet recherchierbar: http://www.presseportal.de

Further inquiry note:

Dr. Achim Plum
Sen. VP Corporate Development
Epigenomics AG
Tel: +49 30 24345 368
achim.plum@epigenomics.com

Branche: Biotechnology
ISIN: DE000A0BVT96
WKN: A0BVT9
Index: Prime All Share, Technology All Share
Börsen: Frankfurt / regulated dealing/prime standard
Berlin / free trade
Hamburg / free trade
Stuttgart / free trade
Düsseldorf / free trade
München / free trade